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Implications for Practice Due to the established connection between GLP-1 agonists and DR, optometrists should err on the side of caution and be in contact with primary care physicians on whether GLP-1/gastric inhibitory polypeptide (GIP) agonists should be prescribed in patients who have existing DR
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69 In comparison, newer oral small-molecule GLP-1 RAs, such as danuglipron and orforglipron, have demonstrated similar efficacy
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